Invitrogen™ DHX16 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530272

Catalog No. PIPA530272

Description

Recommended positive controls: 293T, Raji. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (88%), Pig (100%), Rhesus Monkey (99%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: DHX16
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Dhx16
• Gene Alias: 2410006N22Rik; ATP-dependent RNA helicase #3; DBP2; Ddx16; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16; DEAD/H box 16; DEAH (Asp-Glu-Ala-His) box polypeptide 16; DEAH-box helicase 16; DEAH-box protein 16; Dhx16; KIAA0577; mKIAA0577; Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; PRO2014; Prp2; PRP8; PRPF2; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; RNA helicase
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8449
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.52 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O60231
• Gene Symbols: Dhx16
• Immunogen: Recombinant fragment corresponding to a region within amino acids 624 and 889 of Human DHX16.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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