Invitrogen™ DHX29 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558338

Catalog No. PIPA558338

Description

Immunogen sequence: LQAFSFKTKD IEDAMTNTLL YGGDLHSALD WLCLNLSDDA LPEGFSQEFE EQQPKSRPKF QSPQIQATIS PPLQPKTK Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 95%.

DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.

Specifications

• Antigen: DHX29
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DHX29
• Gene Alias: 3732415M03; ATP-dependent RNA helicase DHX29; AU043276; DDX29; Ddxx; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 29; DEAH (Asp-Glu-Ala-His) box polypeptide 29; DEAH box protein 29; DEAH-box helicase 29; Dhx29; E130202M19Rik; LOC100362324; Nucleic acid helicase DDXx
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54505
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q7Z478
• Gene Symbols: DHX29
• Immunogen: Recombinant protein corresponding to Human DHX29. Recombinant protein control fragment (Product #RP-96813).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG