Invitrogen™ DHX36 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557259

Catalog No. PIPA557259

Description

Immunogen sequence: ERREEQIVQL LNSVQAKNDK ESEAQISWFA PEDHGYGTEV STKNTPCSEN KLDIQEKKLI NQEKKMFRIR NRSYIDRDSE YLLQENEPDG T Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 79%.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to RNA helicase of the DEAH family and may function in sex development and spermatogenesis. It is expressed in testis and is evolutionary conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. DHX36 is required for early embryogenesis.

Specifications

• Antigen: DHX36
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DHX36
• Gene Alias: 2810407E23Rik; AI452301; Asp-Glu-Ala-His; ATP-dependent DNA/RNA helicase DHX36; ATP-dependent RNA helicase DHX36; AU022184; Ddx36; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36; DEAD/H box polypeptide 36; DEAH (Asp-Glu-Ala-His) box polypeptide 36; DEAH box protein 36; DEAH-box helicase 36; DEAH-box protein 36; DHX36; G4 resolvase-1; G4R1; G4-resolvase 1; G4-resolvase-1; KIAA1488; mKIAA1488; Mlel1; MLE-like protein 1; probable ATP-dependent RNA helicase DHX36; RHAU; RNA helicase associated with AU-rich element ARE; RNA helicase associated with AU-rich element protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170506
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H2U1
• Gene Symbols: DHX36
• Immunogen: Recombinant protein corresponding to Human DHX36. Recombinant protein control fragment (Product #RP-96443).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov