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Tocris Bioscience™ Di 4 ANEPPS
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Catalog No. 73245
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73-245 5 mg
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Catalog No. 73-245 Supplier Tocris Bioscience™ Supplier No. 7324/5
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Description

Voltage-sensitive probe; used to detect changes in membrane potential in electrophysiology protocols

Di 4 ANEPPS is a voltage-sensitive dye, also known as an electrochromic probe, which fluoresces in response to change in electrical potential across a cellular membrane. Di 4 ANEPPS fluoresces only when membrane bound; change in electrical potential causes an intramolecular charge transfer and blue-shift in the excitation spectra. Di 4 ANEPPS is commonly used to detect transient changes in membrane potential in excitable cells such as neurons and cardiac cells. Excitation ratio measurements can be used to determine membrane potential.

In model phospholipid membranes Ex/Em maxima are 465/635 nm, however spectral properties are highly dependent on membrane environment.

Specifications

Chemical Name or Material 6-[2-(N,N-Dibutylamino)naphthyl]ethenyl-4 '-pyridinium propanesulfonate
CAS 90134-00-2
Quantity 5 mg
Target Fluorescent Cell Indicators and Sensors
Molecular Formula C28H36N2O3S
Purity 0.9
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