Invitrogen™ H4R3me2a Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102612

Catalog No. PIPA5102612

Description

Antibody detects endogenous levels of Di-Methyl-Histone H4 only when methylated at Arg3.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: H4R3me2a
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H4C1
• Gene Alias: dimethyl H4; di-methyl H4; dimethyl Histone H4; di-methyl Histone H4; Di-Methyl-H4 Arg3; Di-Methyl-H4 R3; Di-Methyl-Histone H4 Arg3; Di-Methyl-Histone H4 R3; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 R3me2a; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/j; H4/K; H4/M; H4/n; H4/O; H4/p; H4-12; H4-16; H4-53; H4Arg3me2; H4Arg3me2a; H4Arg3me2s; H4C1; H4C11; H4c12; H4C13; H4c14; H4C15; H4C2; H4c3; H4c4; H4C5; H4c6; H4c8; H4c9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4M; H4R3; H4R3me2; H4R3me2s; HIST1H4; Hist1h4a; HIST1H4B; HIST1H4C; Hist1h4d; HIST1H4E; Hist1h4f; HIST1H4H; HIST1H4I; Hist1h4j; HIST1H4K; HIST1H4L; Hist1h4m; Hist2h4; HIST2H4A; HIST2H4B; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; histone H4; Histone H4A; Histone H4R3; Histone H4R3me2; Histone H4R3me2a; histone IV, family 2; methyl Histone 3; methyl Histone H3; X04652
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 121504, 319158, 326619, 326620, 8294, 8359, 8363, 8366, 8367, 8370, 97122
• Content And Storage: -20°C
• Form: Liquid

• Applications: ChIP Assay, Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P62805, P62806
• Gene Symbols: H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9
• Immunogen: A synthetic methylated peptide derived from human Di-Methyl-Histone H4 around the methylation site of Arg3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov