Invitrogen™ Diazepam Binding Inhibitor Polyclonal Antibody

Catalog No.	Quantity
PIPA584066	100 μL

Catalog No. PIPA584066 Supplier Invitrogen™ Supplier No. PA584066

Description

Rabbit Polyclonal Antibody

Immunogen sequence: MSQAEFEKAA EEVRHLKTKP SDEEMLFIYG HYKQATVGD Highest antigen sequence indentity to the following orthologs: Mouse - 82%, Rat - 79%.

This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: Diazepam Binding Inhibitor
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.05 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: DBI
• Gene Accession No.: P07108
• Gene Alias: ACBD 1; ACBD1; ACBP; Acoabp3; acyl coenzyme A binding protein; acyl-CoA binding protein; acyl-CoA-binding protein; acyl-Coenzyme A binding domain containing 1; CCK RP; CCKRP; CCK-RP; cholecystokinin-releasing peptide, trypsin-sensitive; Dbi; diazepam binding inhibitor; Diazepam binding inhibitor (GABA receptor modulator acyl-Coenxyme A binding protein); diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein); Diazepam binding inhibitor (GABA receptor modulator, acyl-Coenxyme A binding protein); diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein); diazepam binding inhibitor, acyl-CoA binding protein; diazepam binding inhibitor, splice form 1b; diazepam-binding inhibitor; Endozepine; EP; GABA receptor modulator; LRRGT00046; MGC70414; octadecaneuropeptide; ODN; RNACOABP3; Triakontatetraneuropeptide; Ttn; valium
• Gene Symbols: DBI
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human DBI. Recombinant protein control fragment (Product #RP-103098).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1622
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG