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Dicer Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501561356
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Catalog No. Quantity
50-156-1356 100 μL
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Catalog No. 50-156-1356 Supplier Bethyl Laboratories, Inc Supplier No. A301936A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

DICER1 is a ribonuclease that has been extensively shown to be related to cancer. Small interfering RNAs are generated through DICER, and seem to play important roles in mitosis in normal cells and oncogenesis in mutated cells. DICER1 mutations are associated with blastoma, breast cancer, adenocarcinoma, and pancreatitis. In vision and hearing, DICER1 has been implicated in serious microRNA induced malformations of critical sensory cells. DICER1 is important in myelination and other nervous system protections. Finally, DICER1 is related to cardiovascular diseases, since microRNAs are aberrantly expressed in some pathological conditions.

Specifications

Antigen Dicer
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene DICER1
Gene Accession No. Q8R418, Q9UPY3
Gene Alias DCR1, Dicer, HERNA, KIAA0928
Gene Symbols DICER1
Host Species Rabbit
Immunogen Between 600 and 650
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192119, 23405
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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