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DICER1 Rabbit anti-Human, Polyclonal, liquid, OriGene
SDP

Catalog No. 501684796
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50-168-4796 100 μL
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Catalog No. 50-168-4796 Supplier OriGene Supplier No. TA890110
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Description

Rabbit Polyclonal Antibody

DICER1 is a ribonuclease that has been extensively shown to be related to cancer. Small interfering RNAs are generated through DICER, and seem to play important roles in mitosis in normal cells and oncogenesis in mutated cells. DICER1 mutations are associated with blastoma, breast cancer, adenocarcinoma, and pancreatitis. In vision and hearing, DICER1 has been implicated in serious microRNA induced malformations of critical sensory cells. DICER1 is important in myelination and other nervous system protections. Finally, DICER1 is related to cardiovascular diseases, since microRNAs are aberrantly expressed in some pathological conditions.

Specifications

Antigen DICER1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene DICER1
Gene Accession No. Q9UPY3
Gene Alias DCR1, Dicer, Dicer1e, HERNA, K12H4.8-LIKE, MNG1, RMSE2
Gene Symbols DICER1
Host Species Rabbit
Immunogen Recombit protein of human DICER1
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23405
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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