DIDO1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-6089	Proteintech Group Inc 101831AP150UL	150 μL

Description

The immunogen of this antibody is the C-terminal of isoform 2 of DATF1 (DIDO1).

Dio-1 (Death Inducer-Obliterator-1) is a putative transcription factor that contains two zinc finger motifs. Dio-1 translocates to the nucleus, and activates apoptosis during limb development. Programmed cell death, a highly regulated form of apoptosis, plays an important role in determining the amount of tissue, the shape, and the definition of each digit during limb development. Dio-1 expression is upregulated when an apoptotic signal is detected, and subsequently apoptosis is induced. This process is similar to the expression of NFkB and NGF in response to external signals. Dio-1 expression is suppressed by caspase inhibitors and Bcl-2 expression. This supports the theory that Dio-1 functions in the onset of programmed cell death.

Specifications

• Antigen: DIDO1
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q8C9B9, Q9BTC0
• Gene ID (Entrez): 11083, 23856, 362286
• Immunogen: DIDO1 Fusion Protein Ag0237
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: DIDO1

• Concentration: 0.3 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: BYE1, C20orf158, DATF 1, DATF1, death inducer obliterator 1, DIDO1, DIDO2, DIDO3, DIO 1, DIO1, hDido1, KIAA0333
• Gene Symbols: Dido1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody