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Invitrogen™ DIO2 Polyclonal Antibody
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Catalog No. PIPA518659
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100 μg
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Catalog No. Quantity
PIPA518659 100 μg
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Catalog No. PIPA518659 Supplier Invitrogen™ Supplier No. PA518659
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with human, porcine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine by outer ring deiodination to bioactive 3,3',5-triiodothyronine residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DIO2
Applications Flow Cytometry, Immunohistochemistry (PFA fixed), Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene DIO2
Gene Accession No. Q92813, Q9Z1Y9
Gene Alias 5DII; AI324267; D2; deiodinase, iodothyronine, type 2; deiodinase, iodothyronine, type II; deiodinase-2; deiodonase-2; Dio2; DIOII; iodothyronine type II deiodinase; Itdi2; SelY; thyroxine deiodinase; thyroxine deiodinase, type II; thyroxine type II; TXDI2; Type 2 DI; type 2 iodothyronine deiodinase; type II iodothyronine deiodinase; type-II 5' deiodinase; type-II 5'deiodinase; type-II 5'-deiodinase
Gene Symbols DIO2
Host Species Goat
Immunogen Synthetic peptide sequence (EVKKHQNQEDRC) corresponding to the internal amino acids of DIO2 (aa 181-192).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13371, 1734
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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