Invitrogen™ DIO2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565489

Catalog No. PIPA565489

Description

Immunogen sequence: EWRRMLTSEGL RCVWKSFLLD AYKQVKLGED APNSSVVHVS STEGGDNSGN GTQEKIAEGA TCHLLDFASP ERP Highest antigen sequence identity to the following orthologs - mouse 80%, rat 51%.

The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine by outer ring deiodination to bioactive 3,3',5-triiodothyronine residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: DIO2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DIO2
• Gene Alias: 5DII; AI324267; D2; deiodinase, iodothyronine, type 2; deiodinase, iodothyronine, type II; deiodinase-2; deiodonase-2; Dio2; DIOII; iodothyronine type II deiodinase; Itdi2; SelY; thyroxine deiodinase; thyroxine deiodinase, type II; thyroxine type II; TXDI2; Type 2 DI; type 2 iodothyronine deiodinase; type II iodothyronine deiodinase; type-II 5' deiodinase; type-II 5'deiodinase; type-II 5'-deiodinase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1734
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q92813
• Gene Symbols: DIO2
• Immunogen: Recombinant Human DIO2. Recombinant protein control fragment (Product #RP-106163).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG