Invitrogen™ DIO2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA549631

Catalog No. PA549631

Description

Predicted to react with pig based on sequence homology.

The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine by outer ring deiodination to bioactive 3,3',5-triiodothyronine residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: DIO2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DIO2
• Gene Alias: 5DII; AI324267; D2; deiodinase, iodothyronine, type 2; deiodinase, iodothyronine, type II; deiodinase-2; deiodonase-2; Dio2; DIOII; iodothyronine type II deiodinase; Itdi2; SelY; thyroxine deiodinase; thyroxine deiodinase, type II; thyroxine type II; TXDI2; Type 2 DI; type 2 iodothyronine deiodinase; type II iodothyronine deiodinase; type-II 5' deiodinase; type-II 5'deiodinase; type-II 5'-deiodinase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 13371, 1734
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q92813, Q9Z1Y9
• Gene Symbols: DIO2
• Immunogen: KLH conjugated synthetic peptide between 165-191 amino acids of human DIO2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG