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DIO2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985575
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50-198-5575 100 μL
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Catalog No. 50-198-5575 Supplier Bioss Supplier No. BS3673R
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Rabbit Polyclonal Antibody

The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine by outer ring deiodination to bioactive 3,3′,5-triiodothyronine residues encoded by the UGA codon, which normally signals translation termination. The 3′ UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence , which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

Antigen DIO2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene DIO2
Gene Accession No. Q92813
Gene Alias 5DII; AI324267; D2; deiodinase, iodothyronine, type 2; deiodinase, iodothyronine, type II; deiodinase-2; deiodonase-2; Dio2; DIOII; iodothyronine type II deiodinase; ITDI2; SelY; thyroxine deiodinase, type II; thyroxine type II; TXDI2; Type 2 DI; type 2 iodothyronine deiodinase; Type II iodothyronine deiodinase; type-II 5′ deiodinase; type-II 5′deiodinase; Type-II 5′-deiodinase
Gene Symbols DIO2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human DIO2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1734
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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