Invitrogen™ DIRAS3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596877

Catalog No. PIPA596877

Description

Immunogen sequence: MGNASFGSKE QKLLKRLRLL PALLILRAFK PHRKIRDYRV VVVGTAGVGK STLLHKWASG NFRHEYLPTI ENTYCQLLGC SHGVLSLHIT DSKSGDGNRA LQRHVIARGH AFVLVYSVTK KETLEELKAF YELICKIKGN NLHKFPIVLV GNKSDDTHRE VALNDGATCA MEWNCAFMEI SAKTDVNVQE LFHMLLNYKK KPTTGLQEPE KKSQMPNTTE KLLDKCIIM; Positive Samples: NIH/3T3, Mouse liver, Mouse kidney, Rat liver; Cellular Location: Cell membrane, Cytoplasmic side, Lipid-anchor.

This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.

Specifications

• Antigen: DIRAS3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DIRAS3
• Gene Alias: ARHI; DIRAS family GTP binding RAS like 3; DIRAS family GTPase 3; DIRAS family, GTP-binding RAS-like 3; DIRAS3; Distinct subgroup of the Ras family member 3; GTP-binding protein Di-Ras3; NOEY2; ras homolog gene family, member I; RGD1565168; RHOI; rho-related GTP-binding protein RhoI
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 366733
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.71 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O95661
• Gene Symbols: DIRAS3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-229 of human DIRAS3 (NP_0046661).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG