Invitrogen™ DIRAS3 Polyclonal Antibody

Catalog No.	Quantity
PIPA596877	100 μL

Catalog No. PIPA596877 Supplier Invitrogen™ Supplier No. PA596877

Description

Rabbit Polyclonal Antibody

Immunogen sequence: MGNASFGSKE QKLLKRLRLL PALLILRAFK PHRKIRDYRV VVVGTAGVGK STLLHKWASG NFRHEYLPTI ENTYCQLLGC SHGVLSLHIT DSKSGDGNRA LQRHVIARGH AFVLVYSVTK KETLEELKAF YELICKIKGN NLHKFPIVLV GNKSDDTHRE VALNDGATCA MEWNCAFMEI SAKTDVNVQE LFHMLLNYKK KPTTGLQEPE KKSQMPNTTE KLLDKCIIM; Positive Samples: NIH/3T3, Mouse liver, Mouse kidney, Rat liver; Cellular Location: Cell membrane, Cytoplasmic side, Lipid-anchor.

This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.

Specifications

• Antigen: DIRAS3
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 1.71 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: DIRAS3
• Gene Accession No.: O95661
• Gene Alias: ARHI; DIRAS family GTP binding RAS like 3; DIRAS family GTPase 3; DIRAS family, GTP-binding RAS-like 3; DIRAS3; Distinct subgroup of the Ras family member 3; GTP-binding protein Di-Ras3; NOEY2; ras homolog gene family, member I; RGD1565168; RHOI; rho-related GTP-binding protein RhoI
• Gene Symbols: DIRAS3
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-229 of human DIRAS3 (NP_0046661).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 366733
• Target Species: Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG