Invitrogen™ DJ-1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578362

Catalog No. PIPA578362

Description

Positive Control: 293T, A431, HeLa, HepG2, U87-MG, SK-N-SH, IMR32, SK-N-AS, mouse pancreas, rat pancreas Predicted Reactivity: Pig (100%), Chicken (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.

Specifications

• Antigen: DJ-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Park7
• Gene Alias: CAP1; Contraception-associated protein 1; CTA-215D11.1; dj1; DJ-1; DJ-1 protein; early onset 7; epididymis secretory sperm binding protein Li 67p; fertility protein SP22; FLJ27376; FLJ34360; FLJ92274; HEL-S-67p; hypothetical protein LOC449674; maillard deglycase; Oncogene DJ1; OTTHUMP00000001350; OTTHUMP00000001351; PARK7; PARK7 GENE; PARK7/DJ1; parkinson disease (autosomal recessive, early onset) 7; Parkinson disease 7; Parkinson disease protein 7; Parkinson disease protein 7 homolog; Parkinson disease protein 7 homolog; protein/nucleic acid deglycase DJ-1; parkinson protein 7; Parkinsonism associated deglycase; parkinsonism-associated deglycase; Protein CAP1; protein deglycase DJ-1; protein deglycase DJ-1zDJ-1; Protein DJ-1; protein DJ-1-like protein; protein DJ-1zDJ-1; Protein/nucleic acid deglycase DJ-1; RNA-binding protein regulatory subunit; SP22; zDJ-1; zgc:103725
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11315, 117287, 57320
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O88767, Q99497, Q99LX0
• Gene Symbols: Park7
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human PARK7/DJ1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov