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Invitrogen™ DKK2 Polyclonal Antibody
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Catalog No. PIPA590096
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100 μL
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PIPA590096 100 μL
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Catalog No. PIPA590096 Supplier Invitrogen™ Supplier No. PA590096
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CMVCRRKKKR CHRDGMCCPS TRCNNGICIP VTESILTPHI PALDGTRHRD RNHGHYSNHD LGWQNLGRPH TKMSHIKGHE GDPCLRSSDC IEGFCCARHF WTKICKPVLH QGEVCTKQRK KGSHGLEIFQ RCDCAKGLSC KVWKDATYSS KARLHVCQKI; Positive Samples: A-549, NCI-H460.

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DKK2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.84 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene DKK2
Gene Accession No. Q9UBU2
Gene Alias dickkopf 2; dickkopf 2 homolog; Dickkopf gene 2; dickkopf homolog 1; dickkopf homolog 2; dickkopf homolog 2 (Xenopus laevis); dickkopf homolog 4; dickkopf related protein-2; dickkopf WNT signaling pathway inhibitor 2; dickkopf-2; Dickkopf-related protein 2; DKK2; DKK-2; Dkk4; hDkk-2; mDkk-2; UNQ682/PRO1316
Gene Symbols DKK2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human DKK2 (NP_0552361).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27123
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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