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Invitrogen™ DKK3 Monoclonal Antibody (4G7)
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Catalog No. PIMA515601
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100 μL
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PIMA515601 100 μL
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Catalog No. PIMA515601 Supplier Invitrogen™ Supplier No. MA515601
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Description

Mouse Monoclonal Antibody

MA5-15601 targets DKK3 in indirect ELISA, FACS and WB applications and shows reactivity with Human and Non-human primate samples. The MA5-15601 immunogen is purified recombinant fragment of human DKK3 expressed in E. Coli. MA5-15601 detects DKK3 which has a predicted molecular weight of approximately 38kDa.

DKK3, like DKK1, DKK2, and DKK4, possesses an N-terminal signal peptide and 2 conserved cysteine-rich domains, which are separated by a linker region and contain 10 cysteine residues each. The second cysteine region has a putative lipid-binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin-type proteases. Northern blot analysis revealed wide expression of the DKK3 transcript, with highest expression in heart, brain, and spinal cord. In situ hybridization reveals highest expression in mouse brain, eye, and heart.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DKK3
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 4G7
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene DKK3
Gene Accession No. Q9UBP4
Gene Alias AW061014; C87148; Dickkopf; dickkopf 3; dickkopf 3 homolog; Dickkopf gene 3; dickkopf homolog 3; dickkopf homolog 3 (Xenopus laevis); dickkopf WNT signaling pathway inhibitor 3; Dickkopf3; dickkopf-3; Dickkopf-related protein 3; DKK 3; Dkk3; dkk-3; hDkk 3; hDkk-3; hhDkk3; mDkk-3; p29; regulated in glioma; Reic; RIG; RIG-like 5-6; RIG-like 7-1; UNQ258/PRO295; Xenopus
Gene Symbols DKK3
Host Species Mouse
Immunogen Purified recombinant fragment of human DKK3 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27122
Target Species Human, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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