DLC1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA528443

Catalog No. PIPA528443

Description

Recommended positive controls: H1299, HeLaS3, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (100%), Dog (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.

Specifications

• Antigen: DLC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Dlc1
• Gene Alias: A730069N07Rik; ARHGAP 7; ARHGAP7; deleted in liver cancer 1; deleted in liver cancer 1 protein; Deleted in liver cancer 1 protein homolog; deleted in liver cancer 1 variant 2; deleted in liver cancer variant 4; DLC 1; DLC1; Dlc-1; DLC1 Rho GTPase activating protein; DLC1 Rho GTPase activating protein; rho GTPase-activating protein 7; FLJ21120; HP; HP protein; KIAA1723; p122 RhoGAP; p122-RhoGAP; rho GTPase activating protein 7; rho GTPase-activating protein 7; RhoGAP; Rho-GTPase-activating protein 7; rho-type GTPase-activating protein 7; STARD 12; STARD12; StAR-related lipid; StAR-related lipid transfer (START) domain containing 12; stAR-related lipid transfer protein 12; START domain-containing protein 12; transfer protein 12; unm_sa1141
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10395
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.84 mg/mL
• Formulation: PBS with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96QB1
• Gene Symbols: Dlc1
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 43 of Human DLC1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG