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Invitrogen™ DLD Polyclonal Antibody
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Catalog No. PIPA592447
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100 μL
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PIPA592447 100 μL
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Catalog No. PIPA592447 Supplier Invitrogen™ Supplier No. PA592447
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ADQPIDADVT VIGSGPGGYV AAIKAAQLGF KTVCIEKNET LGGTCLNVGC IPSKALLNNS HYYHMAHGKD FASRGIEMSE VRLNLDKMME QKSTAVKALT GGIAHLFKQN KVVHVNGYGK ITGKNQVTAT KADGGTQVID TKNILIATGS EVTPFPGITI DEDTIVSSTG ALSLKKVPEK MVVIGAGVIG VELGSVWQRL GADVTAVEFL GHVGGVGIDM EISKNFQRIL QKQGFKFKLN TKVTGATKKS DGKIDVSIEA ASGGK; Positive Samples: MCF7, BT-474, K-562, 293T, Mouse kidney, Mouse skeletal muscle, Mouse liver; Cellular Location: Mitochondrion matrix.

This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DLD
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.28 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Dld
Gene Accession No. O08749, P09622
Gene Alias aei; after eight protein; branched chain alpha-keto acid dehydrogenase complex subunit E3; deltaD; deltaD transmembrane protein; delta-like protein D; diaphorase; dihydrolipoamide dehydrogenase; dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex); dihydrolipoamide: NAD+ oxidoreductase; dihydrolipoyl dehydrogenase mitochondrial-like protein; dihydrolipoyl dehydrogenase, mitochondrial; DLD; DLDD; DLDH; E3; E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex; GCSL; Glycine cleavage system L protein; glycine cleavage system protein L; LAD; lipoamide dehydrogenase; lipoamide dehydrogenase precursor; lipoamide reductase; lipoyl dehydrogenase; LOW QUALITY PROTEIN: dihydrolipoyl dehydrogenase, mitochondrial; mitochondrial Dihydrolipoyl dehydrogenase-like protein; OTTHUMP00000206744; OTTHUMP00000206746; OTTHUMP00000206748; OTTHUMP00000206749; PH; PHE 3; PHE3; QflA-16416; QtsA-11266; sc:d0402; unnamed protein product
Gene Symbols Dld
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 36-300 of human DLDH/DLDH/DLDH/DLD (NP_0000992).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13382, 1738
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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