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DLK1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 50559617 Shop All Proteintech Group Inc Products
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50-559-617 150 μL
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Catalog No. 50-559-617 Supplier Proteintech Group Inc Supplier No. 106361AP150UL
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Rabbit Polyclonal Antibody

This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdomice; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.

Specifications

Antigen DLK1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.34 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene DLK1
Gene Accession No. P80370, Q09163
Gene Alias DLK, DLK 1, DLK1, FA1, pG2, Pref 1, PREF1, Protein delta homolog 1, ZOG
Gene Symbols DLK1
Host Species Rabbit
Immunogen DLK1 Fusion Protein Ag0991
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114587, 13386, 8788
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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