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DMAP1 Polyclonal Antibody, Active Motif™
SDP

Catalog No. 501993610
Encompass
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50-199-3610 100 μL
50-199-3611 10 μL
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Catalog No. 50-199-3610 Supplier Active Motif Supplier No. 61675
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Rabbit Polyclonal Antibody

DNA methyltransferase 1-associated protein 1 (DMAP1) is involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The protein also specifically potentiates DAXX-mediated repression of glucocorticoid receptor-dependent transcription. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. DMAP1 is found in a wide variety of living organisms from yeasts to humans. The human DMAP1 gene is localized on chromosome 1p34.

Specifications

Antigen DMAP1
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene DMAP1
Gene Accession No. Q9NPF5
Gene Alias 1500016M21Rik; BOS_3636; DKFZp686L09142; Dmap1; Dmtap1; DNA methyltransferase 1 associated protein 1; DNA methyltransferase 1-associated protein 1; DNMAP1; DNMT1 associated protein 1; DNMT1 associated protein-1; DNMT1-associated protein 1; DNMTAP1; EAF2; FLJ11543; KIAA1425; MAT1-mediated transcriptional repressor; MEAF2; mKIAA1425; Mmtr; RP5-891H21.2; SWC4
Gene Symbols DMAP1
Host Species Rabbit
Immunogen This antibody was raised against a peptide within the C-terminal region of human DMAP1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55929
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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