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Invitrogen™ DMP1 Polyclonal Antibody
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Catalog No. PIPA557956
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100 μL
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PIPA557956 100 μL
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Catalog No. PIPA557956 Supplier Invitrogen™ Supplier No. PA557956
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QYIYRLAGGF SRSTGKGGDD KDDDEDDSGD DTFGDDDSGP GPKDRQEGGN SRLGSDEDSD DTIQASEESA PQGQDSAQDT TSE Highest antigen sequence identity to the following orthologs: Mouse - 61%, Rat - 63%.

Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DMP1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Dmp1
Gene Accession No. Q13316
Gene Alias AG1; ARHP; ARHR; AV020965; dentin matrix acidic phosphoprotein 1; dentin matrix protein 1; DENTMAT; Dmp; DMP 1; Dmp1; DMP-1; MGC130441; PP; serine rich acidic phosphoprotein
Gene Symbols Dmp1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DMP1. Recombinant protein control fragment (Product #RP-96691).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1758
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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