DMPO Mouse anti-Chemical, Clone: N1664A, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527550
DescriptionThe formation of free radicals and other highly reactive oxygen species has been implicated in the pathogenesis of many disease states. The ability to identify these species is crucial, and spin trapping has accomplished this goal. DMPO (5,5-dimethyl-1-pyrroline N-oxide) is one of the least toxic to cells and animals, and possesses convenient pharmacokinetics (uptake, distribution, metabolism and excretion) in biological systems. Recent studies have determined that nitric oxide may substantially affect the quantitative determination of DMPO adducts, and therefore extra caution is required when studying generation of these species in the presence of nitric oxide or its radicals. DMPO adducts can be generated with protein and DNA radicals.
|PBS with 50% glycerol and 0.09% sodium azide; pH 7.4|
|5,5-dimethyl-2-(8-octanoic acid)-1-pyrroline N oxide, DMPO nitrone adduct, 55 dimethyl 1 pyrroline N oxide nitrone adduct|
|5,5-dimethyl-2-(8-octanoic acid)-1-pyrrolone-N-oxide conjugated to Ovalbumin|
|ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot|
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