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Tocris Bioscience™ DMXAA
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Catalog No. 560150
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560110 10 mg
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Catalog No. 560150 Supplier Tocris Bioscience™ Supplier No. 5601/50
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Description

mSTING agonist; induces antitumor immunological responses

DMXAA is a mSTING agonist; selective for mouse STING over human STING. Induces IFN-β and cytokine production from bone marrow-derived dendritic cells. Causes tumor regression following intratumoral administration in mouse tumor models. Induces an adaptive immune response to reduce systemic tumor growth and provides immunological memory against autologous tumor re-challenge. Also antiviral.

Specifications

Chemical Name or Material 5,6-Dimethyl-9-oxo-9 H-xanthene-4-acetic acid
CAS 117570-53-3
Quantity 50 mg
Target STING Agonists
Molecular Formula C17H14O4
Formula Weight 282.29
Purity 99%
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