Invitrogen™ DNA Ligase III Monoclonal Antibody (1F3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA123191

Catalog No. MA123191

Description

Recommended positive controls: 293T, A431, HeLa, HepG2. The predicted molecular weight of MA1-23191 is 100 kDa.

There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair and recombination. DNA Ligase III gene product migrates as a 100 kDa (a-form) protein in somatic tissues, is ubiquitously expressed and complexes with XRCC-1 and a 97 kDa (beta form) protein that is found in testis. DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.

Specifications

• Antigen: DNA Ligase III
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P49916, P97386
• Gene Symbols: LIG3
• Immunogen: Recombinant full-length human DNA Ligase III-b.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Chicken
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunoprecipitation, Neutralization, Western Blot, Proximity Ligation Assay, Immunocytochemistry
• Clone: 1F3
• Conjugate: Unconjugated
• Gene: LIG3
• Gene Alias: D11Wsu78e; DNA ligase (ATP) 3; DNA ligase 3; DNA ligase III; hypothetical protein; LIG2; LIG3; ligase II, DNA, ATP-dependent; ligase III, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 3; Unknown (protein for MGC:134139)
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 16882, 3980, 417530
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid