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Invitrogen™ DNA Ligase III Monoclonal Antibody (1F3)
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Catalog No. MA123191
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100 μL
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Catalog No. Quantity
MA123191 100 μL
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Catalog No. MA123191 Supplier Invitrogen™ Supplier No. MA123191
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Description

Mouse Monoclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2. The predicted molecular weight of MA1-23191 is 100 kDa.

There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair and recombination. DNA Ligase III gene product migrates as a 100 kDa (a-form) protein in somatic tissues, is ubiquitously expressed and complexes with XRCC-1 and a 97 kDa (beta form) protein that is found in testis. DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DNA Ligase III
Applications Immunoprecipitation, Neutralization, Western Blot, Proximity Ligation Assay, Immunocytochemistry
Classification Monoclonal
Clone 1F3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene LIG3
Gene Accession No. P49916, P97386
Gene Alias D11Wsu78e; DNA ligase (ATP) 3; DNA ligase 3; DNA ligase III; hypothetical protein; LIG2; LIG3; ligase II, DNA, ATP-dependent; ligase III, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 3; Unknown (protein for MGC:134139)
Gene Symbols LIG3
Host Species Mouse
Immunogen Recombinant full-length human DNA Ligase III-b.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16882, 3980, 417530
Target Species Human, Mouse, Chicken
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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