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Invitrogen™ DNA Ligase III Polyclonal Antibody
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Catalog No. PIPA521480
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100 μL
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Catalog No. Quantity
PIPA521480 100 μL
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Catalog No. PIPA521480 Supplier Invitrogen™ Supplier No. PA521480
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2. Predicted reactivity: Mouse (92%), Rat (91%), Pig (94%), Rhesus Monkey (97%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair and recombination. DNA Ligase III gene product migrates as a 100 kDa (a-form) protein in somatic tissues, is ubiquitously expressed and complexes with XRCC-1 and a 97 kDa (beta form) protein that is found in testis. DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DNA Ligase III
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.81 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene LIG3
Gene Accession No. P49916
Gene Alias D11Wsu78e; DNA ligase (ATP) 3; DNA ligase 3; DNA ligase III; hypothetical protein; LIG2; LIG3; ligase II, DNA, ATP-dependent; ligase III, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 3; Unknown (protein for MGC:134139)
Gene Symbols LIG3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human DNA ligase III. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3980
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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