Invitrogen™ DNA Ligase III Recombinant Rabbit Monoclonal Antibody (5I7T5)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA551407

Catalog No. FEMA551407

Description

Immunogen sequence: IASRCTANDL KCIIRLIKHD LKMNSGAKHV LDALDPNAYE AFKASRNLQD VVERVLHNAQ EVEKEPGQRR ALSVQASLMT PVQPMLAEAC KSVEYAMKKC P.

There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair and recombination. DNA Ligase III gene product migrates as a 100 kDa (a-form) protein in somatic tissues, is ubiquitously expressed and complexes with XRCC-1 and a 97 kDa (beta form) protein that is found in testis. DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.

Specifications

• Antigen: DNA Ligase III
• Classification: Recombinant Monoclonal
• Concentration: 0.09 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P49916, P97386
• Gene Symbols: LIG3
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human DNA Ligase III/LIG3 (NP_039269.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Format: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 5I7T5
• Conjugate: Unconjugated
• Gene: LIG3
• Gene Alias: D11Wsu78e; DNA ligase (ATP) 3; DNA ligase 3; DNA ligase III; hypothetical protein; LIG2; LIG3; ligase II, DNA, ATP-dependent; ligase III, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 3; Unknown (protein for MGC:134139)
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16882, 303369, 3980
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid
• Isotype: IgG