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DNA Polymerase beta Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988620
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100 μL
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50-198-8620 100 μL
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Catalog No. 50-198-8620 Supplier Bioss Supplier No. BS8525R
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Description

Rabbit Polyclonal Antibody

DNA polymerase beta comprises an amino-terminal 8- kDa domain and a carboxy-terminal 31- kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase beta, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates beta-pol level. DNA polymerase beta fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells.

Specifications

Antigen DNA Polymerase beta
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene POLB
Gene Accession No. P06746
Gene Alias A430088C08Rik; BOS_23903; DNA pol beta; DNA polymerase beta; DNA polymerase beta subunit; DNA-directed DNA polymerase beta; LOW QUALITY PROTEIN: DNA polymerase beta; MGC125976; POL B; Pol beta; POLB; polb.S; polymerase (DNA directed), beta; polymerase (DNA directed), beta S homeolog; polymerase (DNA) beta; polymerase B; polymerase-beta; wu:fa97a05; XELAEV_18020165mg; zgc:109924
Gene Symbols POLB
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human DNA Polymerase beta.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5423
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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