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DNA Polymerase Kappa/POLK Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982545
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50-198-2545 100 μL
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Catalog No. 50-198-2545 Supplier Bioss Supplier No. BS13019R
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Description

Rabbit Polyclonal Antibody

External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass.

Specifications

Antigen DNA Polymerase Kappa/POLK
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene POLK
Gene Accession No. Q9UBT6
Gene Alias BOS_10072; DinB homolog 1; DINB protein; DINB1; DINP; DNA damage-inducible protein b; DNA polymerase kappa; DNA-directed DNA polymerase kappa; Polk; POLQ; polymerase (DNA directed) kappa; polymerase (DNA directed), kappa; polymerase (DNA) kappa
Gene Symbols POLK
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human DNA Polymerase Kappa/POLK.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51426
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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