Invitrogen™ DNAI1 Recombinant Rabbit Monoclonal Antibody (4Y6Q1)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542832

Catalog No. PIMA542832

Description

Positive test controls include: Mouse lung, Mouse testis, Rat testis. Immunogen sequence: MIPASAKAPH KQPHKQSISI GRGTRKRDED SGTEVGEGTD EWAQSKATVR PPDQLELTDA ELKEEFTRIL TANNPHAPQN IVRYSFKEGT YKPIGFVNQL AVHYTQVGNL IPKDSDEGRR QHYRDELVAG SQESVKVISE TGNLEEDEEP KELETEPGSQ TDVPAAGAAE KVTEEELMTP KQPKERKLTN QFNFSERASQ.

Eukaryotic cells rely on actin and microtubule-based protein motors to generate intracellular movements. These protein motors contain specialized domains that hydrolyze ATP to produce force and movement along a cytoskeletal polymer (actin in the case of myosin family and microtubules in the case of the kinesin family and dyneins). Dynein has been implicated in cytoplasmic motile functions, including chromosomal movement, retrograde organelle and axonal transport, the endocytic pathway, and the organization of the Golgi apparatus. In all cell types, dynein has the same basic structures and is composed of two or three distinct heavy chains (~450 kDa), three intermediate chains (70-125 kDa), and at least four light chains (15-25 kDa).

Specifications

• Antigen: DNAI1
• Classification: Recombinant Monoclonal
• Concentration: 1.1 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q5XIL8
• Gene Symbols: DNAI1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Dynein intermediate chain 1 (Q9UI46).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 4Y6Q1
• Conjugate: Unconjugated
• Gene: DNAI1
• Gene Alias: 1110066F04Rik; axonemal dynein intermediate chain 1; b2b1526Clo; BB124644; CILD1; DIC1; Dnai1; Dnaic1; dynein axonemal intermediate chain 1; Dynein intermediate chain 1, axonemal; dynein, axonemal, intermediate chain 1; dynein, axonemal, intermediate polypeptide 1; I79_025143; ICS; ICS1; immotile cilia syndrome 1; MGC26204; PCD; RP11-296L22.2; testis tissue sperm-binding protein Li 87P
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 500442
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

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