DNAJB2 Monoclonal Antibody (OTI4D12), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-3776	100 μL
50-254-1329	30 μL

Catalog No. 50-167-3776 Supplier OriGene Supplier No. TA502760

Description

Mouse Monoclonal Antibody

The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJB2 (DnaJ homolog subfamily B member 2), also known as HSJ1 or HSPF3, is expressed almost exclusively in the brain, with the highest levels in the frontal cortex and hippocampus. Two isoforms are produced due to alternative splicing.

Specifications

• Antigen: DNAJB2
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: OTI4D12
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: DNAJB2
• Gene Accession No.: P25686
• Gene Alias: CMT2T, DSMA5, HSJ-1, HSJ1, HSPF3
• Gene Symbols: DNAJB2
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human DNAJB2 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3300
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1