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Invitrogen™ DNAJC13 Polyclonal Antibody
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Catalog No. PIPA557872
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100 μL
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PIPA557872 100 μL
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Catalog No. PIPA557872 Supplier Invitrogen™ Supplier No. PA557872
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VTPGGFDQIN PATNRVLCSY DYRNIEGFVD LSDYQGGFCI LYGGFSRLHL FASEQREEII KSAIDHAGNY IGISLRIRKE PLEFEQYLNL RF Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 92%.

DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans. It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system. Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles. DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DNAJC13
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DNAJC13
Gene Accession No. O75165
Gene Alias D030002L11Rik; DnaJ (Hsp40) homolog, subfamily C, member 13; DnaJ domain-containing protein RME-8; DnaJ heat shock protein family (Hsp40) member C13; dnaJ homolog subfamily C member 13; DNAJC13; Gm1124; j-domain containing protein, required for endocytosis; KIAA0678; mKIAA0678; PARK21; receptor mediated endocytosis RME-8; required for receptor-mediated endocytosis 8; Rme8; RME-8
Gene Symbols DNAJC13
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DNAJC13. Recombinant protein control fragment (Product #RP-96342).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23317
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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