Invitrogen™ DNAJC13 Recombinant Superclonal™ Antibody

Rabbit Recombinant Superclonal Antibody

Supplier:  Invitrogen™ 711808

Catalog No. PI711808

Description

This antibody is predicted to react with Monkey, Cat, Goat, and Sheep. Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called Recombinant polyclonal antibody, this product is now rebranded as Recombinant Superclonal™ antibody. The physical product and the performance remain unchanged.

DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans. It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system. Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles. DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor.

Specifications

• Antigen: DNAJC13
• Classification: Recombinant Superclonal
• Conjugate: Unconjugated
• Gene: DNAJC13
• Gene Alias: D030002L11Rik; DnaJ (Hsp40) homolog, subfamily C, member 13; DnaJ domain-containing protein RME-8; DnaJ heat shock protein family (Hsp40) member C13; dnaJ homolog subfamily C member 13; DNAJC13; Gm1124; j-domain containing protein, required for endocytosis; KIAA0678; mKIAA0678; PARK21; receptor mediated endocytosis RME-8; required for receptor-mediated endocytosis 8; Rme8; RME-8
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 102119164, 23317
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: O75165
• Gene Symbols: DNAJC13
• Immunogen: Protein corresponding to human DNAJC13 (aa1301-aa1354 GST fusion).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Cynomolgus Monkey
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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