DNAJC2/MPP11 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-7606	Proteintech Group Inc 119711AP150UL	150 μL

Description

EIF4EBP1 is one member of a family of translation repressor proteins. It directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Specifications

• Antigen: DNAJC2/MPP11
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P54103, Q7TQ20, Q99543
• Gene ID (Entrez): 116456, 22791, 27000
• Immunogen: DNAJC2/MPP11 Fusion Protein Ag2594
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: DNAJC2

• Concentration: 0.13 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: DNAJC2, M phase phosphoprotein 11, MPP11, ZRF1, ZUO1, Zuotin related factor 1
• Gene Symbols: DNAJC2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody