Invitrogen™ DNAJC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA545040

Catalog No. PIPA545040

Description

Peptide sequence: EINEQIRKEK EEAEARMRQA SKNTEKSTGG GGNGSKNWSE DDLQLLIKAV Sequence homology: Cow: 86%; Dog: 92%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 93%.

EIF4EBP1 is one member of a family of translation repressor proteins. It directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Specifications

• Antigen: DNAJC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Dnajc2
• Gene Alias: (rat homolog) mouse id-associated protein 1; AU020218; DnaJ (Hsp40) homolog, subfamily C, member 2; DnaJ heat shock protein family (Hsp40) member C2; dnaJ homolog subfamily C member 2; DnaJ homolog subfamily C member 2, N-terminally processed; Dnajc2; Gliosarcoma-related antigen MIDA1; Id associate 1; Mida1; Mouse Id associate 1; M-phase phosphoprotein 11; MPHOSPH11; MPP11; Unknown (protein for MGC:139161); ZRF1; Zrf2; ZUO1; zuotin related factor 1; zuotin related factor 2; zuotin-related factor 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27000
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q99543
• Gene Symbols: Dnajc2
• Immunogen: Synthetic peptide directed towards the C-terminal of human DNAJC2 (aa 417-466).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG