Invitrogen™ DNase II Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA130778

Catalog No. PIPA130778

Description

Recommended positive controls: Human spleen tissue lysate. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DNase II is a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.

Specifications

• Antigen: DNase II
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DNASE2
• Gene Alias: acid DNase; deoxyribonuclease; Deoxyribonuclease II alpha; deoxyribonuclease II, lysosomal; deoxyribonuclease-2-alpha; DNase II alpha; DNase II, lysosomal; DNASE2; Dnase2a; DNL; Dnl2; lysosomal DNase II; R31240_2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1777
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide; pH 7.4
• Gene Accession No.: O00115
• Gene Symbols: DNASE2
• Immunogen: Peptide corresponding to aa 347- 360 of human DNase II precursor (accession no. AF047016).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov