Invitrogen™ DNASE2B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100482

Catalog No. PIPA5100482

Description

Antibody detects endogenous levels of total DNASE2B.

The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: DNASE2B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DNASE2B
• Gene Alias: deoxyribonuclease DLAD; deoxyribonuclease II beta; Deoxyribonuclease-2-beta; DLAD; DNA for uricase; DNase II beta; DNase II-like acid DNase; Dnase2b; DNase2-like acid DNase; DNaseII-like acid DNase; endonuclease DLAD; lysosomal DNase II; UOX
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 58511, 59296
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8WZ79, Q9QZK9
• Gene Symbols: DNASE2B
• Immunogen: A synthesized peptide derived from human DNASE2B(Accession Q8WZ79), corresponding to amino acid residues Y302-G352.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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