Invitrogen™ DNASE2B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531391

Catalog No. PIPA531391

Description

Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Bovine (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: DNASE2B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DNASE2B
• Gene Alias: deoxyribonuclease DLAD; deoxyribonuclease II beta; Deoxyribonuclease-2-beta; DLAD; DNA for uricase; DNase II beta; DNase II-like acid DNase; Dnase2b; DNase2-like acid DNase; DNaseII-like acid DNase; endonuclease DLAD; lysosomal DNase II; UOX
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 58511
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.96 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8WZ79
• Gene Symbols: DNASE2B
• Immunogen: Recombinant protein encompassing a sequence within the center region of human DNASE2B. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov