Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIMA521436

Invitrogen™ DNMBP Monoclonal Antibody (1H2)
GREENER_CHOICE

Catalog No. PIMA521436
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA521436 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIMA521436 Supplier Invitrogen™ Supplier No. MA521436
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

Peptide Sequence: TKKPFERKTI DRQSARKPLL GLPSYMLQSE ELRASLLARY PPEKLFQAER NFNAAQDLDV SLLEGDLVGV IKKKDPMGSQ NRWLIDNGVT KGFVYSSFLK.

The Dynamin Binding Protein (DNMBP) gene is located on chromosome 10 and has been implicated in Alzheimer's disease due to its role in regulating the actin cytoskeleton and synaptic vesicle pools, which are critical for proper neuronal function and memory performance. DNMBP mRNA expression levels are shown to be lower in Alzheimer's brains, suggesting its potential role in cognitive decline. Genetic studies have linked DNMBP to late-onset Alzheimer's disease (AD) through its single nucleotide polymorphisms (SNPs) such as rs11190305 and rs3740058, although the results show variability across different ethnic populations regarding its association with AD risk. Additionally, research on aged rats demonstrated a correlation between DNMBP expression and long-term memory performance, indicating its significance in maintaining cognitive functions during aging.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DNMBP
Applications ELISA, Western Blot
Classification Monoclonal
Clone 1H2
Concentration 0.2-1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene DNMBP
Gene Accession No. Q6XZF7
Gene Alias 2410003L07Rik; 2410003M15Rik; ARHGEF36; Dnmbp; dynamin binding protein; dynamin-binding protein; Kiaa1010; Scaffold protein Tuba; TUBA
Gene Symbols DNMBP
Host Species Mouse
Immunogen DNMBP (AAH41628, 491 a.a. ~ 590 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23268
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG3 κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.