Invitrogen™ Dnmt2 Monoclonal Antibody (OTI8H10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527483

Catalog No. PIMA527483

Description

Dnmt2 Monoclonal Antibody for Western Blot

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: Dnmt2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O14717, O55055
• Gene Symbols: TRDMT1
• Immunogen: Human recombinant protein fragment corresponding to amino acids 84-293 of TRDMT1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI8H10
• Conjugate: Unconjugated
• Gene: TRDMT1
• Gene Alias: DMNT2; DNA (cytosine-5)-methyltransferase-like protein 2; DNA cytosine-5 methyltransferase 2; DNA methyltransferase 2; DNA methyltransferase homolog HsaIIP; DNA methyltransferase homolog MmuIIP; DNA methyltransferase-2; DNA MTase homolog HsaIIP; DNA MTase homolog MmuIIP; Dnmt2; M.HsaIIP; m.MmuIIP; Met2; met-2; MHSAIIP; PUMET; RNMT1; Rnmt2; RP11-406H21.1; Trdmt1; tRNA (cytosine(38)-C(5))-methyltransferase; tRNA (cytosine-5-)-methyltransferase; tRNA aspartic acid methyltransferase 1
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13434, 1787
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid