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Invitrogen™ DNMT2 Polyclonal Antibody
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Catalog No. PIPA557884
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100 μL
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PIPA557884 100 μL
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Catalog No. PIPA557884 Supplier Invitrogen™ Supplier No. PA557884
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RVLELYSGVG GMHHALRESC IPAQVVAAID VNTVANEVYK YNFPHTQLLA KTIEGITLEE FDRLSFDMIL MSPPCQPFTR IGRQGDMTDS RT Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 86%.

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DNMT2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TRDMT1
Gene Accession No. O14717
Gene Alias DMNT2; DNA (cytosine-5)-methyltransferase-like protein 2; DNA cytosine-5 methyltransferase 2; DNA methyltransferase 2; DNA methyltransferase homolog HsaIIP; DNA methyltransferase homolog MmuIIP; DNA methyltransferase-2; DNA MTase homolog HsaIIP; DNA MTase homolog MmuIIP; Dnmt2; M.HsaIIP; m.MmuIIP; Met2; met-2; MHSAIIP; PUMET; RNMT1; Rnmt2; RP11-406H21.1; Trdmt1; tRNA (cytosine(38)-C(5))-methyltransferase; tRNA (cytosine-5-)-methyltransferase; tRNA aspartic acid methyltransferase 1
Gene Symbols TRDMT1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DNMT2. Recombinant protein control fragment (Product #RP-102756).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1787
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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