Invitrogen™ DNMT2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557885

Catalog No. PIPA557885

Description

Immunogen sequence: KIESVHPQKY AMDVENKIQE KNVEPNISFD GSIQCSGKDA ILFKLETAEE IHRKNQQDSD LSVKMLKDFL EDDTDVNQYL LPPKSLLRYA L Highest antigen sequence identity to the following orthologs: Mouse - 62%, Rat - 60%.

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: DNMT2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRDMT1
• Gene Alias: DMNT2; DNA (cytosine-5)-methyltransferase-like protein 2; DNA cytosine-5 methyltransferase 2; DNA methyltransferase 2; DNA methyltransferase homolog HsaIIP; DNA methyltransferase homolog MmuIIP; DNA methyltransferase-2; DNA MTase homolog HsaIIP; DNA MTase homolog MmuIIP; Dnmt2; M.HsaIIP; m.MmuIIP; Met2; met-2; MHSAIIP; PUMET; RNMT1; Rnmt2; RP11-406H21.1; Trdmt1; tRNA (cytosine(38)-C(5))-methyltransferase; tRNA (cytosine-5-)-methyltransferase; tRNA aspartic acid methyltransferase 1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1787
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O14717
• Gene Symbols: TRDMT1
• Immunogen: Recombinant protein corresponding to Human DNMT2. Recombinant protein control fragment (Product #RP-103678).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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