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Invitrogen™ DNMT3B Polyclonal Antibody
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Catalog No. 01674425
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500 μg
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Catalog No. Quantity
01-674-425 500 μg
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Catalog No. 01-674-425 Supplier Invitrogen™ Supplier No. PA19542
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Description

Chicken Polyclonal Antibody

PA1-9542 detects DNMT3L in human samples. PA1-9542 has been successfully used in Western blot procedures. By Western blot, PA1-9542 detects a 47 kDa protein representing DNMT3L. PA1-9542 immunogen is a purified recombinant DNMT3L.1 corresponding to the chromosome 21 gene (Human).

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DNMT3B
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Dnmt3b
Gene Accession No. Q9UBC3
Gene Alias DNA (cytosine-5-)-methyltransferase 3 beta; DNA (cytosine-5)-methyltransferase 3B; DNA methyltransferase 3 beta; DNA methyltransferase 3B; DNA methyltransferase HsaIIIB; DNA methyltransferase MmuIIIB; DNA MTase HsaIIIB; DNA MTase MmuIIIB; Dnmt3; DNMT3B; ICF; ICF1; M.HsaIIIB; m.MmuIIIB; MGC1090; MmuIIIB
Gene Symbols Dnmt3b
Host Species Chicken
Immunogen Purified recombinant DNMT3L.1 corresponding to the chromosome 21 gene (Human).
Purification Method IgY Fraction
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1789
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgY
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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