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Dnmt3b Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989907
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100 μL
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50-198-9907 100 μL
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Catalog No. 50-198-9907 Supplier Bioss Supplier No. BS20680R
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Description

Rabbit Polyclonal Antibody

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

Specifications

Antigen Dnmt3b
Applications Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH
Gene Dnmt3b
Gene Accession No. Q9UBC3
Gene Alias DNA (cytosine-5-)-methyltransferase 3 beta; DNA (cytosine-5)-methyltransferase 3B; DNA methyltransferase 3 beta; DNA methyltransferase 3B; DNA methyltransferase HsaIIIB; DNA methyltransferase MmuIIIB; DNA MTase HsaIIIB; DNA MTase MmuIIIB; Dnmt3; DNMT3B; ICF; ICF1; M.HsaIIIB; m.MmuIIIB; MGC1090; MmuIIIB
Gene Symbols Dnmt3b
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Dnmt3b.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1789
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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