DOCK8 Mouse anti-Human, Clone: OTI12D7, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF801863

Catalog No. 50-166-5748

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors. DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome.

Specifications

• Antigen: DOCK8
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: DOCK8
• Gene Alias: HEL-205, MRD2, ZIR8
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 81704
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI12D7
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q8NF50
• Gene Symbols: DOCK8
• Immunogen: Human recombit protein fragment corresponding to amino acids 84-405 of human DOCK8 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1