Invitrogen™ DOCK8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA538049

Catalog No. PIPA538049

Description

A recommended positive control is EL4 cell lysate. Multiple isoforms of DOCK8 are known to exist.

The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors. DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome.

Specifications

• Antigen: DOCK8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Dock8
• Gene Alias: 1200017A24Rik; 5830472H07Rik; A130095G14Rik; AI461977; dedicator of cytokinesis 8; dedicator of cytokinesis protein 8; Dock8; epididymis luminal protein 205; HEL-205; MRD2; ZIR8
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 499337, 76088, 81704
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q8C147, Q8NF50
• Gene Symbols: Dock8
• Immunogen: 17 amino acid peptide near the carboxy terminus of human DOCK8.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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