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Invitrogen™ DOK1 Recombinant Rabbit Monoclonal Antibody (JE54-52)
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Catalog No. PIMA536191
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Quantity:
100 μL
Catalog No. Quantity
PIMA536191 100 μL
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Catalog No. PIMA536191

Supplier: Invitrogen™ MA536191

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Description

Rabbit Recombinant Monoclonal Antibody

DOK1 Recombinant Monoclonal Antibody for Western Blot

DOK1 (P62dok, Docking protein 1) is believed to be a mainly cytoplasmic adaptor protein which down-regulates mitogen-activated protein kinase activation, inhibits cell proliferation and transformation, and promotes cell spreading and cell migration. DOK1 is a major substrate for many tyrosine kinases including c-kit, v-abl, vFPS, EGF, and PDGF. Upon phosphorylation by kinases, DOK1 forms a complex with ras GTPase-activating protein. Phosphorylation on tyrosine residues by the insulin receptor kinase results in the negative regulation of the insulin signaling pathway. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DOK1
Applications Western Blot
Classification Recombinant Monoclonal
Clone JE54-52
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene DOK1
Gene Accession No. Q4QQV2, Q99704
Gene Alias AW557123; Docking protein 1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); Dok; DOK 1; DOK1; Dok-1; Downstream of tyrosine kinase 1; downstream of tyrosine kinase-1; MGC117395; MGC138860; p240; p62 dok; p62(dok); p62DOK; pp62; TLP1; TP1; TROVE domain family; TROVE1; VAULT2
Gene Symbols DOK1
Host Species Rabbit
Immunogen Recombinant protein within Human DOK1 aa 360-481.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1796, 312477
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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