Invitrogen™ DOK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589616

Catalog No. PIPA589616

Description

Immunogen sequence: MGDGAVKQGF LYLQQQQTFG KKWRRFGASL YGGSDCALAR LELQEGPEKP RRCEAARKVI RLSDCLRVAE AGGEASSPRD TSAFFLETKE RLYLLAAPAA ERGDWVQAIC LLAFPGQRKE LSGPEGKQSR PCMEENELYS SAVTVGPHKE FAVTMRPTEA SERCHLRGSY TLRAGESALE LWGGPEPGTQ LYDWPYRFLR RFGRDKVTFS FEAGRRCVSG EGNFEFETRQ GNEIFLALEE AISAQKNAAP ATPQPQPATI; Positive Samples: THP-1, Mouse lung.

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 from CML cells.

Specifications

• Antigen: DOK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DOK2
• Gene Alias: docking protein 2; docking protein 2, 56kD; docking protein 2, 56kDa; Dok2; Dok-2; DokR; Dok-R; dok-related protein; Downstream of tyrosine kinase 2; Frip; IL-Four Receptor Interacting Protein; IL-four receptor-interacting protein; LOW QUALITY PROTEIN: docking protein 2; docking protein 2; p56 dok-2; p56(dok-2); p56DOK; p56dok-2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13449, 9046
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.26 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O60496, O70469
• Gene Symbols: DOK2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DOK2 (NP_0039652).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG