Invitrogen™ DOK4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA549857

Catalog No. PA549857

Description

The antibody detects endogenous levels of total DOK4 protein.

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. [UniProt].

Specifications

• Antigen: DOK4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DOK4
• Gene Alias: docking protein 4; Dok4; Downstream of tyrosine kinase 4; insulin receptor substrate 5; IRS5; IRS-5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114255, 55715
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8TEW6, Q99KE3
• Gene Symbols: DOK4
• Immunogen: Synthesized peptide derived from internal of human DOK4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG