Invitrogen™ DOK4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563190

Catalog No. PIPA563190

Description

Immunogen sequence: QRLEKYPDEK SVCLRGCPKV TEISNVKCVT RLPKETKRQA VAIIFTDDSA RTFTCDSEL Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. [UniProt].

Specifications

• Antigen: DOK4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DOK4
• Gene Alias: docking protein 4; Dok4; Downstream of tyrosine kinase 4; insulin receptor substrate 5; IRS5; IRS-5
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55715
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8TEW6
• Gene Symbols: DOK4
• Immunogen: Recombinant protein corresponding to Human DOK4. Recombinant protein control fragment (Product #RP-101658).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG